Objectives To evaluate the feasibility of recruitment, appointment adherence, intervention compliance, acceptance and comprehensibility, in addition to retention rate and data completeness.An ancillary aim was to describe within-group changes in the secondary outcome measures (patient-reported and performance-based).Design A single-centre, three-ar
Factors related to survival outcomes following orbital exenteration: a retrospective, comparative, case series
Abstract Background Orbital exenteration is a disfiguring procedure that aims to achieve local control.It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition.It Horse Saddles is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration.Methods Thi
The influence of endocrine disrupting chemicals
On a daily basis, everyone is exposed to many chemical compounds that have been classified as endocrine disrupting chemicals (EDCs).These are natural and artificially produced substances that are widely available in the environment today.The aim of the study is to determine the effect of endocrine disrupting chemicals on hormonal processes occurrin
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women.Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients remains low, demonstrating the necessity for novel treatments.One strategy Saddle Pads to improve tr
Epigenetic Aspects and Prospects in Autoimmune Hepatitis
The observed risk of autoimmune hepatitis exceeds its genetic risk, and epigenetic factors that alter gene expression without changing nucleotide sequence may help explain the disparity.Key objectives of this review are to describe the epigenetic modifications that affect gene expression, discuss how they can affect autoimmune hepatitis, and indica